The fact that the complement system is activated during immune-complex glomerular disease has been known for nearly 50 years. Detection of complement deposition in the glomerulus using immunochemistry ...

A gamma-globulin factor in the serum of patients with systemic lupus erythematosus that reacts with isolated cell nuclei 1 or nucleoprotein 2,3 has been detected in many ways. 4 The standard method of ...