自2007年邓子新院士团队发现DNA上第六元素：硫元素以来，他们就瞄准了这一倍受关注的研究领域，近期这一研究组又接连发表了DNA硫修饰研究方面的几项重大成果，充分显示了我国在此前沿新兴领域持之以恒的开拓性和创新性。为了更深入了解这一研究成果 ...

5月2日，国际权威学术期刊《自然》在线发表了来自中科院上海生物化学与细胞生物学研究所徐国良院士联合复旦大学唐惠儒教授和中科院武汉水生生物研究所黄开耀研究员等多个课题组合作完成的研究成果“A vitamin-C-derived DNA modification catalysed by an algal TET homologue ...

Your DNA holds the blueprint to build your body, but it’s a living document: Adjustments to the design can be made by epigenetic marks. Cataloguing these marks and how they work is important for ...

A new study shows that the RNA cap-modifying enzyme PCIF1 drives tumor growth and radioresistance, and that removing its m6Am mark on MSH2 activates the cGAS-STING immune pathway to boost radiotherapy ...

Discover the latest articles and news in related subjects. Currently, therapies routinely used for the treatment of SLE, or that are in development, aim to reduce the production of autoantibodies by ...

"Are they the same thing, just with different names?" You might feel that way when you hear about genetic modification and ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Scheme showing the structure of cytosine, 5-methylcytosine, and 5-hydroxymethylcytosine. Adding a methyl group to the DNA base cytosine represses gene expression in mammalian cells. To remove the ...

This is read by an automated voice. Please report any issues or inconsistencies here. Epigenetic aging clocks measure chemical alterations to DNA to determine the functional age of human cells and ...

Maintaining the stability of the genome is essential for all organisms, and it is not surprising that damage to DNA has been proposed as an explanation for multiple chronic diseases. 1–5 Conserving a ...