The eukaryotic cell cycle orchestrates the orderly duplication and segregation of genetic material through distinct phases—G₁ (growth and monitoring), S (DNA synthesis), G₂ (preparation for division) ...

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study. The work solves a mystery that has long puzzled biologists. A ...

Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers. The work, published Jan.

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library—your genome, which totals more than 3 ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...