Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

A team led by Raju Tomer, professor of biological sciences at Columbia University, has created a new design for microscopes ...

As a mouse explores its environment, millions of neurons across the brain fire in sync. To study only a small subsection at a time would be to miss the forest for the trees, but powerful microscopes ...

Electron microscopes are used to visualize the structure of solids, molecules, or nanoparticles with atomic resolution. However, most materials are not static. Rather, they interact, move, and reshape ...

QIScope: When imaging low protein levels in live cells on the high-sensitivity QIScope, bioluminescence (blue) significantly outperforms fluorescence (green). (Courtesy: Ruyu Ma - Helmholtz Munich) A ...

A project at the University of Colorado Boulder (CU Boulder) has developed a new way to image neural activity in live animals. Described in Biomedical Optics Express, the device is a miniaturized ...

A newly described technology improves the clarity and speed of using two-photon microscopy to image synapses in the live brain. The brain's ability to learn comes from "plasticity," in which neurons ...

A light microscope image of a planktonic foraminifera (bottom right) surrounded by thin strands of its cytoplasm that extend into the surrounding environment. This living specimen had recently been ...