Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered ...

Liquid–liquid phase separation is a process in which a uniform solution separates into two coexisting liquid phases. In living cells, it governs the formation of membrane-less compartments that ...

In mammalian cells, besides nuclei, mitochondria are the only semi-autonomous organelles possessing own DNA organized in the form of nucleoids. While eukaryotic nuclear DNA compaction, chromatin ...

BACKGROUND: Congenital heart disease (CHD), the most common birth defect and a leading cause of infant mortality, is ...

In a new paper published in Molecular Biology of the Cell, the Allain lab (IBC) reported that the phase separation of the SARS-CoV-2 N protein strongly depends on the chosen buffer and pH. For example ...