Single-cell analysis has transformed our understanding of germ cell development by resolving the diversity and dynamics of individual cells within the testis and ovary. Employing high-throughput ...

Single-cell transcriptomics has revolutionised our understanding of the cellular complexity underlying neurodegenerative disorders by enabling the high-resolution profiling of individual brain cells.

Researchers increasingly turn to single-cell sequencing to answer a range of biological questions, with published single-cell data increasing year over year. As its popularity rises, so does the need ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Bulk RNA sequencing has advanced transcriptomic analysis across diverse biological systems, but averaging gene expression across cell populations can obscure important cellular differences.

Kelly Parliament, staff application scientist at Beckman Coulter Life Sciences, discusses how automation is improving the efficiency of single-cell transcriptomic workflows. Single-cell ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...